IL12/23 (p40), IL23, IL12 (p70) Antikörper

Produktnummer ABIN6963860

Dieser Maus Monoklonal Antikörper erkennt spezifisch in ELISA und ELISpot. Er zeigt eine Reaktivität gegenüber Human und Non-Human Primate und wurde in 4+ Publikationen erwähnt.

Kurzübersicht für IL12/23 (p40), IL23, IL12 (p70) Antikörper (ABIN6963860)

Target: IL12/23 (p40), IL23, IL12 (p70)

Reaktivität: Human, Non-Human Primate

Wirt: Maus

Klonalität: Monoklonal

Applikation: ELISA, ELISpot

Klon: MT86-221

Produktdetails

Spezifität: Native and recombinant p40 subunit of IL-12 and IL-23. The antibodies recognize p40 monomer, p40 homodimer, IL-12 p70 heterodimer (p40+p35) and IL-23 heterodimer (p40+p19).

Kreuzreaktivität (Details): The monoclonal antibodies cross-react with the p40 subunit of IL-12 and IL-23 from non-human primates.

Produktmerkmale: These monoclonal antibodies enable specific detection of the p40 subunit of human IL-12 and IL-23 in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples

Aufreinigung: Purified from in vitro cultures by protein G affinity chromatography.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant human IL-23

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Is recommended as capture mAbs in ELISpot, FluoroSpot, and ELISA for analysis of: IL-12/-23 (p40) in combination with mAb ABIN6963861 and ABIN7448304 .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Haltbarkeit: 18 months

Referenzen

Pourakbari, Hosseinpour Sadeghi, Mahmoudi, Parvaneh, Keshavarz Valian, Mamishi: "Evaluation of interleukin-12 receptor β1 and interferon gamma receptor 1 deficiency in patients with disseminated BCG infection." in: Allergologia et immunopathologia, Vol. 47, Issue 1, pp. 38-42, (2019) (PubMed).

Iaconelli, Lemetais, Kechaou, Chain, Bermúdez-Humarán, Langella, Gervais, Beney: "Drying process strongly affects probiotics viability and functionalities." in: Journal of biotechnology, Vol. 214, pp. 17-26, (2016) (PubMed).

Myers, Cooper, Kem, Stavrakis, Kosanke, Shevach, Fairweather, Stoner, Cox, Cunningham: "Cardiac myosin-Th17 responses promote heart failure in human myocarditis." in: JCI insight, Vol. 1, Issue 9, (2016) (PubMed).

Mohanram, Sköld, Bächle, Pathak, Spetz: "IFN-α induces APOBEC3G, F, and A in immature dendritic cells and limits HIV-1 spread to CD4+ T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 7, pp. 3346-53, (2013) (PubMed).

Antigendetails

Target: IL12/23 (p40), IL23, IL12 (p70)

Gen-ID: 3592, 3593